IgA Nephropathy is common in young men, mostly caused by incentives of upper respiratory tract infection, diarrhea, urinary tract infections and etc. In the early stage, microscopic hematuria appears and then gross hematuria, proteinuria and occult blood. The symptoms are different in different degree of the disease. In fact, IgA Nephropathy is mainly caused by a series of immune responses due to the patient’s reduced immune system and it makes a large number of immune complex depositted in glomerular capillary loops and mesangial areas and the inherent cells will be damaged because of hypoxia and ischemia and then inflammatory factors are attracted, the inflammatory cells are infiltrated and inflammatory response occurs. If it can’t be controlled, the inherent cells will be changed and produce toxicity and toxic growth factors, resulting in renal fibrosis and a series of vicious circle to damage the kidneys.
How to treat IgA Nephropathy in children? In order to solve this problem, after years of effort and combining international advanced technology, the experts finally developed stem cell transplant therapy to eliminate the pain of patients and anxiety of parents. Stem cell transplant is the latest development in medical community after summing up the disadvantages of a variety of medicine. Stem cells are extracted from the baby’s umbilical cord blood. Through intravenous transfusion, they can reach the patient’s body directly. Stem cells have the function of recognizing renal injury and by the function of homing, they can reach the lesions to repair inherent cells that are not completely damaged and generate desired cells. In this way, they can alleviate the state of ischemia and hypoxia of renal microcirculation, remove the sediment and wastes and repair the basement membrane. After these functions become normal, the adverse symptoms such as occult blood, urine protein will disappear, preventing inflammatory response and the process of renal fibrosis.
With the innovation of technology, it’s not difficult to treat IgA Nephropathy in children. So the parents needn’t worry too much. As long as your children can grow up in a good environment, establish self-confidence and receive active treatment, the chance of getting better is very big. And the effect of stem cell transpalnt therapy is very obvious and ideal.